Police are appealing for witnesses to come forward following a break-in at the Campbelltown Lifeline store.
Lifeline employees arrived at work about 5.30am this morning to discover several items were stolen, including a sum of cash.
The employees contacted police and an investigation was launched.
A NSW Police Media spokeswoman said forensic officers dusted the scene for fingerprints today.
Anyone who can assist Campbelltown police is urged to call the station on 4620 1199.
Lifeline Macarthur did not respond to the Advertiser's request for comment.